LDL-cholesterol lowering effect of a generic product of simvastatin compared to simvastatin (Zocor™) in Thai hypercholesterolemic subjects – a randomized crossover study, the first report from Thailand

Table 3 Characteristics of the subjects in both groups after crossover and continuation of drug for further 8 weeks

Parameters	mean ± standard deviation (90 % confidence interval)		P-value
	1^st group (N = 21)	2^nd group (N = 16)
Total cholesterol (mg/dL)	200.30 ± 36.86	182.40 ± 17.24	NS
	(187.07–213.53)	(175.31–189.49)
HDL (mg/dL)	47.40 ± 9.64	49.40 ± 10.38	NS
	(43.94–50.86)	(45.13–53.67)
Triglyceride (mg/dL)	142.40 ± 62.54	127.40 ± 58.40	NS
	(119.95–164.85)	(103.38–151.42)
LDL (mg/dL)	124.40 ± 31.70	107.50 ± 14.65	NS
	(113.02–135.78)	(101.48–113.52)
SGOT (U/L)	25.10 ± 7.96	23.90 ± 9.50	NS
	(22.24–27.96)	(19.99–27.81)
SGPT (U/L)	37.60 ± 22.32	30.60 ± 21.79	NS
	(29.59–45.61)	(21.64–39.56)
CPK (U/L)	106.20 ± 42.49	118.40 ± 42.35	NS
	(90.95–121.45)	(100.98–135.82)